'Serious blow' for England after Atkinson goes off due to a hamstring issue.
The pace bowler increased the injury concerns plaguing England after leaving the playing area on the second morning of the Boxing Day Test against Australia.
The pace bowler felt a problem in his left leg immediately following a delivery in his spell on Saturday.
Team management indicated the 27-year-old felt some "soreness" and was to take time away from the action for further assessment "in the coming hours".
The concluding match of the tour in Sydney begins at the end of the week.
The English side has been without key quicks Mark Wood due to knee trouble and Jofra Archer because of a side injury on this Ashes tour.
Matthew Fisher was brought into the squad to provide backup.
Atkinson struggled in the opening two Tests, taking just a handful of scalps.
He was dropped from the previous Test, then recalled for the fourth Test in the playing XI.
The county bowler showed better form in Melbourne, bagging two scalps in Australia's first innings, before adding 28 with the bat among just a trio of England players who passed ten runs.
Following a brief spell at the end of day one, he returned for the second day's play and dismissed the nightwatchman edging to the keeper.
However, on the final ball of that over, he delivered a variation to Travis Head and promptly felt at his leg.
Atkinson returned to the side for the fourth Ashes Test after being left out the Adelaide game.
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