The Monarch has taped a first-hand account regarding his journey with cancer, scheduled for transmission as part of this year's annual cancer awareness drive, organised by medical research organisations and a television broadcaster.
Official sources stated the King would reflect on his "recovery journey" as a individual battling cancer, in a recorded address on this Friday at the evening slot.
The address, recorded at a royal residence recently, will highlight the vital significance of preventative health checks to increase the likelihood more people catch the illness at an initial point.
This represents a uncommon insight on the medical condition of the Sovereign, who has been in a course of therapy since his condition was announced in early last year. However, it is believed doubtful the King will disclose his particular diagnosis.
The Stand Up To Cancer initiative each year raises funds for clinical trials and patient care and prompts people to get check-ups to increase the odds of an timely detection.
The King's public discussion about his condition, and managing the disease, has been intended to raise awareness and to get more people to get tested - and this will be escalated with this unique direct participation.
Up until now the King's primary strategy to his cancer has been to keep working, upholding a hectic timetable despite his frequent sessions of care, and he appears not to have desired to be defined by his diagnosis.
This year has seen the 77-year-old Monarch, embarking on several overseas trips, such as visits to Italy and Canada, and hosting the highest tally of official guests to the UK for almost 40 years, which included the German president last week.
Friday evening's awareness programme on Channel 4, hosted by presenters like a team of famous hosts, will encourage people not to be afraid of getting health screenings.
The hosts have been affected by cancer - Davina McCall revealed last month she had undergone surgery for the disease, while Clare Balding was overcame the illness in the past. Comedian Hills has previously mentioned his parent, who had stomach cancer and then later leukaemia.
The show will target the approximate 9m people in the UK who health organisations state are not compliant with NHS screening schemes, with an digital tool to let people determine if they are eligible for tests for several common cancers.
In an bid to explain screenings and show the benefit of early diagnosis there will be a live broadcast from cancer clinics at Addenbrooke's and Royal Papworth hospitals in Cambridge.
"My aim is to reduce the stigma out of cancer screening and prove all people that they are not isolated in this," commented Davina McCall.
Currently in the UK, there are three publicly available checks - for major health concerns - available to eligible individuals.
A new lung cancer screening programme is also being slowly rolled out for people at potential risk of being diagnosed with the illness, primarily aimed at people of a certain age, who currently smoke or used to.
Men may enquire about prostate screenings, but there is not a universal scheme in place.
The charity campaign, which has collected £113m over the past decade, is financing dozens of clinical trials with many patients.
King Charles, in a address for dignitaries at a event for related organisations in April, had referred to understanding the "intimidating and at times alarming situation" for patients and their families.
But he noted his first-hand encounter of living with cancer had revealed that "the darkest moments of sickness can be alleviated by the greatest compassion," as he praised those who looked after cancer patients.
The Palace has not revealed what kind of cancer the King has, or the medical care he has undergone. The King's cancer was identified following he had had a medical treatment.
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